Rabbit Polyclonal COX4I1 Antibody
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms.
| 规格 | 价格 | 库存 |
|---|---|---|
| 50ul | 1800.00 | 现货 |
| 100ul | 3200.00 | 现货 |
基本信息
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名称：兔多克隆COX IV-1抗体 描述：Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. 克隆：多克隆 纯化方式：Affinity purification 宿主：Rabbit/IgG 浓度：1mg/ml 别名：COX4I1;COX IV-1;COX4;COX4-1;COXIV;COXIV-1;COX IV 种属反应性：Human，Mouse，Rat 经测试应用：WB，IF/ICC 分子量：17kDa 抗原：Recombinant fusion protein of human COX IV (NP_001852.1). 应用： WB：1:500-2000 IF/ICC：1:50-200 存储形式：Liquid 存储液：PBS with 0.02% sodium azide,50% glycerol,pH7.3. 储存温度：-20℃
Western blot analysis of extracts of various cell lines, using COX IV Antibody.
Immunofluorescence analysis of U2OS cells using COX IV antibody.
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| 存储温度 | -20℃ |
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