PNU-74654
PNU-74654是Wnt/β-catenin通路的的抑制剂
CAS NO.：113906-27-7
| 规格 | 价格 | 库存 |
|---|---|---|
| 5mg | 500.00 | 现货 |
| 10mg | 800.00 | 现货 |
| 25mg | 1500.00 | 现货 |
| 50mg | 2800.00 | 现货 |
基本信息
|
The Wnt signaling pathway is integral to normal biological processes and inappropriately active in many cancers.PNU 74654 binds to β-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway.Treatment of human adrenocortical cell lines with PNU 74654 significantly reduced expression of several Tcf/β-catenin target genes. |
|
| CAS | 113906-27-7 |
| 分子量 | 320.34 |
| 分子式 |
C19H16N2O3 |
| 溶剂 | DMSO |
| 纯度 | 99% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 3.1217 mL | 15.6084 mL | 31.2168 mL |
| 5 mM | 0.6243 mL | 3.1217 mL | 6.2434 mL |
| 10 mM | 0.3122 mL | 1.5608 mL | 3.1217 mL |
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