Costunlide
((+)-Costunolide; Costus lactone)(+)-Costunolide is an inhibitor of osteoclast differentiation, acting as an anti-inflammatory and anti-oxidant agent. It is a sesquiterpene lactone which mediates apoptosis.
CAS NO.：553-21-9
| 规格 | 价格 | 库存 |
|---|---|---|
| 10mg | 600.00 | 现货 |
| 20mg | 900.00 | 现货 |
| 50mg | 1600.00 | 现货 |
基本信息
|
Costunolide has antipyretic, anti-inflammatory, anti-oxidant, anti-carcinogenic and anti-fungal activities, it possesses normo-glycemic and hypolipidemic activity. Costunolide inhibits RANKL-induced osteoclast differentiation by suppressing RANKL-mediated c-Fos transcriptional activity; it inhibits IL-1beta gene expression by blocking the activation of MAPKs and DNA binding of AP-1; it also induces the ROS-mediated mitochondrial permeability transition and resultant cytochrome c release, |
|
| CAS | 553-21-9 |
| 分子量 | 232.32 |
| 分子式 |
C15H20O2 |
| 溶剂 | DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 4.3044 mL | 21.5220 mL | 43.0441 mL |
| 5 mM | 0.8609 mL | 4.3044 mL | 8.6088 mL |
| 10 mM | 0.4304 mL | 2.1522 mL | 4.3044 mL |
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