Rabbit Monoclonal FOXO1A Antibody
FKHR (for forkhead in rhabdomyosarcoma) and FKHRL1 are members of the forkhead family of transcription factors. Transcriptional activation of FKHR proteins is regulated by the serine/threonine kinase Akt1, which phosphorylates FKHRL1 and results in FKHRL1 associating with 14-3-3 proteins and being retained in the cytoplasm. Induction of apoptosis or withdrawal of growth factors stimulates dephosphorylation and nuclear translocation of FKHR proteins, leading to FKHR-induced gene-specific transcriptional activation. FKHR, also designated forkhead box protein O1A (FOXO1), is a ubiquitously expressed protein that shuttles between the cytoplasm and nucleus.
| 规格 | 价格 | 库存 |
|---|---|---|
| 50ul | 1800.00 | 现货 |
| 100ul | 3200.00 | 现货 |
基本信息
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名称：兔单克隆FOXO1抗体 描述：FKHR (for forkhead in rhabdomyosarcoma) and FKHRL1 are members of the forkhead family of transcription factors. Transcriptional activation of FKHR proteins is regulated by the serine/threonine kinase Akt1, which phosphorylates FKHRL1 and results in FKHRL1 associating with 14-3-3 proteins and being retained in the cytoplasm. Induction of apoptosis or withdrawal of growth factors stimulates dephosphorylation and nuclear translocation of FKHR proteins, leading to FKHR-induced gene-specific transcriptional activation. FKHR, also designated forkhead box protein O1A (FOXO1), is a ubiquitously expressed protein that shuttles between the cytoplasm and nucleus. 克隆：单克隆 别称： FKH 1 antibody FKH1 antibody FKHR antibody Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma) antibody Forkhead box O1 antibody Forkhead box protein O1 antibody Forkhead box protein O1A antibody Forkhead in rhabdomyosarcoma antibody Forkhead, Drosophila, homolog of, in rhabdomyosarcoma antibody FoxO transcription factor antibody foxo1 antibody FOXO1_HUMAN antibody FOXO1A antibody OTTHUMP00000018301 antibody 纯化方式：Protein A affinity purified. 宿主：Rabbit/IgG 种属反应性：Human，Mouse，Rat 经测试应用：WB，IHC-P，IF/ICC 浓度：1mg/ml 预测分子量：70kDa（实际观察：100kDa） RRID： AB_3069795 抗原：Synthetic peptide within Human FOXO1A aa 301-350 / 655. 阳性对照：THP-1 cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, HeLa, NIH/3T3, human tonsil tissue, human breast carcinoma tissue, mouse brain tissue, mouse heart tissue, rat brain tissue, rat heart tissue. 应用： WB：1:1000-2000 IHC-P：1:50-100 IF/ICC： 1:50-100 存储形式：Liquid 存储液：1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. 储存温度：-20℃
Western blot analysis of FOXO1A on different lysates with Rabbit anti-FOXO1A antibody at 1/5,000 dilution.
Immunocytochemistry analysis of HeLa cells labeling FOXO1A with Rabbit anti-FOXO1A antibody at 1/100 dilution.
Immunohistochemical analysis of paraffin-embedded rat heart tissue with Rabbit anti-FOXO1A antibody at 1/1,000 dilution.
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| 存储温度 | -20℃ |
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