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MitoQ

  (Mitoquinone)
目录号: PC-61034

Mitoquinonemesylate是一种靶向线粒体的抗氧化剂,防止氧化损伤。

CAS NO.:444890-41-9

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规格 价格 库存
5mg 1500.00 现货
10mg 2500.00 现货

基本信息

Mitoquinone is a mitochondria-targeted antioxidant designed to accumulate within mitochondria in vivo in order to protect against oxidative damage. Mitoquinone (MitoQ) is a mitochondria-targeted antioxidant.The optimal doses for Mitoquinone (MitoQ) and DecylTPP treatment are selected from dose-response experiments during 4-h cold storage (CS). The potential protective benefits of Mitoquinone treatment against CS injury are tested initially using MitoSOX Red, a mitochondrial-targeted fluorescent dye that measures mitochondrial superoxide generation. Normal rat kidney (NRK) cells exposed to CS result in a ~2-fold increase in fluorescence due to mitochondrial superoxide compared with untreated cells. Mitoquinone offers significant protection against CS-induced mitochondrial superoxide generation; whereas the control compound DecylTPP does not offer any protection. Mitoquinone treatment markedly decreases mitochondrial superoxide generation, whereas kidneys treated with DecylTPP have comparable levels of mitochondrial superoxide to kidneys exposed to CS alone.

CAS 444890-41-9
分子量 583.72
分子式

C37H44O4P

溶剂

DMSO

纯度 98%
存储温度 -20℃

相关说明文档

储备液配置

浓度 体积 质量
1mg 5mg 10mg
1 mM 1.7132 mL 8.5658 mL 17.1315 mL
5 mM 0.3426 mL 1.7132 mL 3.4263 mL
10 mM 0.1713 mL 0.8566 mL 1.7132 mL
注:请根据所选浓度进行配置储备液,配置好储备液后进行分装低温保存,避免反复冻融!PCM提供多种溶剂,如:DMSO(PC-57930);玉米油(PC-86094);棉籽油(PC-30875)等

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