Triptolide
This product is isolated and purified from the herb of Tripterygium wilfordii Hook.f.
CAS NO.：38748-32-2
| 规格 | 价格 | 库存 |
|---|---|---|
| 2mg | 650.00 | 现货 |
| 5mg | 1200.00 | 现货 |
| 10mg | 2000.00 | 现货 |
基本信息
|
Triptolide has immunosuppressive, anti-inflammatory, and anti-cancer activities, it induces apoptosis in tumor cells by blocking NF-KB activation and sensitizing tumor cells for TNF-a induced programmed cell death, it inhibits TGF-β1-induced cell proliferation and migration of rat airway smooth muscle cells, by suppressing Smad signaling and NF-κB ,respectively. Triptolide is an inhibitor of heat shock factor (HSF1), inhibits HSP90-CDC37 binding and induces acetylation of HSP90, and also inhibits MDM2 expression in a dose-dependent manner with IC50 values range from 47 to 73 nM. |
|
| CAS | 38748-32-2 |
| 分子量 | 360.4 |
| 分子式 |
C20H24O6 |
| 溶剂 | DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 2.7747 mL | 13.8735 mL | 27.7469 mL |
| 5 mM | 0.5549 mL | 2.7747 mL | 5.5494 mL |
| 10 mM | 0.2775 mL | 1.3873 mL | 2.7747 mL |
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