Chelidonine
Chelidonine is an isoquinoline alkaloid isolated from Chelidonium majus L., causes G2/M arrest and induces caspase-dependent and caspase-independent apoptosis, with anticancer and antiviral activity。
CAS NO.：476-32-4
| 规格 | 价格 | 库存 |
|---|---|---|
| 1mg | 800.00 | 现货 |
| 5mg | 1880.00 | 现货 |
| 10mg | 3200.00 | 现货 |
基本信息
|
Chelidonine is a promising model compound for overcoming MDR and for enhancing cytotoxicity of chemotherapeutics, especially against leukaemia cells, its efficacy needs to be confirmed in animal models. Chelidonine may be a potential therapeutic agent against metastasis of invasive human cancer cells, exhibits anti‑migratory and anti‑invasive effects in MDA‑MB‑231 cells, by suppressing COL‑I‑induced integrin signaling, through inhibiting the formation of the IPP complex and subsequent down‑regulation of IPP downstream signaling molecules, such as Akt and ERK1/2. |
|
| CAS | 476-32-4 |
| 分子量 | 353.37 |
| 分子式 | C₂₀H₁₉NO₅ |
| 溶剂 | DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 2.8299 mL | 14.1495 mL | 28.2990 mL |
| 5 mM | 0.5660 mL | 2.8299 mL | 5.6598 mL |
| 10 mM | 0.2830 mL | 1.4149 mL | 2.8299 mL |
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