Cinobufagin
(Cinobufagine)Cinobufagine is a major component of cinobufacini (huachansu), is an important cardenolidal steroid. Cinobufagine was shown to exhibit potent anti-cancer effects.
CAS NO.：470-37-1
| 规格 | 价格 | 库存 |
|---|---|---|
| 5mg | 1000.00 | 现货 |
| 10mg | 1900.00 | 现货 |
| 20mg | 3500.00 | 现货 |
基本信息
|
Cinobufagin, a kind of Chinese materia medica with antitumor effect, is widely used in clinical practice, especially in anti-liver cancer, it also has anti-hepatitis B virus activity . Cinobufagin inhibits the proliferation and induces apoptosis, may be related to the mitochondria-mediated pathway and GSK-3β/NF-κB pathway. Cinobufagin can significantly relieve cancer pain in mice and raised their pain threshold, mainly upregulating the expression levels of β -END and μ -OR in the hind paw tumor and adjacent tissue.Cinobufagin and bufalin exhibit cardiotonic and natriuretic activities, they also have inhibitory effects on steroidogenesis of aldosterone and cortisol. |
|
| CAS | 470-37-1 |
| 分子量 | 442.54 |
| 分子式 | C₂₆H₃₄O₆ |
| 溶剂 | DMSO |
| 纯度 | 95% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 2.2597 mL | 11.2984 mL | 22.5968 mL |
| 5 mM | 0.4519 mL | 2.2597 mL | 4.5194 mL |
| 10 mM | 0.2260 mL | 1.1298 mL | 2.2597 mL |
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