Alogliptin Benzoate
(SYR 322)Alogliptin Benzoate (SYR-322) 是一种有效的、具有选择性口服活性的 DPP-4 的抑制剂
CAS NO.：850649-62-6
| 规格 | 价格 | 库存 |
|---|---|---|
| 10mg | 850.00 | 现货 |
| 50mg | 3000.00 | 现货 |
| 100mg | 4200.00 | 现货 |
基本信息
|
Alogliptin is an orally bioavailable dipeptidyl peptidase 4 (DPP-4) inhibitor (IC50 = 6.9 nM) that is selective for DPP-4 over DPP-2, DPP-8, DPP-9, prolyl endopeptidase, fibroblast activation protein (FAP), and tryptase (IC50s = >100,000 nM).It does not inhibit cytochrome P450 enzymes and does not block the human ether-a-go-go-related gene (hERG) channel when used at concentrations up to 30 μM.2 Alogliptin inhibits DPP-4 activity in vivo in rats, dogs, and cynomolgus monkeys (EC50s = 3.4, 4.9, and 5.6 ng/ml, respectively, in plasma). |
|
| CAS | 850649-62-6 |
| 分子量 | 461.51 |
| 分子式 |
C25H27N5O4 |
| 溶剂 |
DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 2.1668 mL | 10.8340 mL | 21.6680 mL |
| 5 mM | 0.4334 mL | 2.1668 mL | 4.3336 mL |
| 10 mM | 0.2167 mL | 1.0834 mL | 2.1668 mL |
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