产品背景：C-X-C motif chemokine 1 (CXCL1) also named Growth-regulated oncogene alpha (GROα), which is a chemokine of the intercrine alpha family. CXCL1 is a 7.5 kDa protein containing 68 amino acid residues. CXCL1 is often expressed in immune cells such as macrophage and neutrophils. CXCL1 plays an important role with immune responses and cancer progression. CXCL1 activates the cell signal transduction with casepas1 that affects the cell proliferation, differentiation and migration.

蛋白编码：P12850

别名：Growth-regulated alpha protein;C-X-C motif chemokine 1;Platelet-derived growth factor-inducible protein KC;Secretory protein N51;Cxcl1;Gro; Gro1; Mgsa; Scyb1；GRO-α

分子量：The protein has a calculated MW of 7.45 kDa. The protein migrates below 11 kDa under reducing condition (SDS-PAGE analysis).

表达系统：Escherichia coli

纯度：>95% as determined by SDS-PAGE.

内毒素：<0.1 EU per 1 μg of the protein by the LAL method.

活性：Measure by its ability to chemoattract human THP1 cells. Chemotactic activity was observed at a concentration of 200 ng/mL.

序列：NELRCQCLQTMAGIHLKNIQSLKVLPSGPHCTQTEVIATLKNGREACLDPEAPLVQKIVQKMLKGVPK.

产品形式：The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0.

干粉复溶：

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.

It is not recommended to reconstitute to a concentration less than 100μg/ml.

Dissolve the lyophilized protein in distilled water.

Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

保存条件：Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.

Reconstituted protein solution can be stored at 2-8°C for 2-7 days.

Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.