Rabbit Monoclonal STING/TMEM173 antibody
Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
| 规格 | 价格 | 库存 |
|---|---|---|
| 50ul | 2200.00 | 现货 |
| 100ul | 4000.00 | 现货 |
基本信息
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名称：兔单克隆Glyt1抗体 描述：Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway. 克隆：单克隆 别称：endoplasmic reticulum IFN stimulator antibody Endoplasmic reticulum interferon stimulator antibody ERIS antibody FLJ38577 antibody hMITA antibody hSTING antibody Mediator of IRF3 activation antibody MITA antibody Mitochondrial mediator of IRF3 activation antibody MPYS antibody N terminal methionine proline tyrosine serine plasma membrane tetraspanner antibody NET23 antibody Stimulator of interferon genes antibody Stimulator of interferon genes protein antibody STING antibody TM173_HUMAN antibody Tmem173 antibody Transmembrane protein 173 antibody 纯化方式：Protein A affinity purified. 宿主：Rabbit/IgG 种属反应性：Human，Mouse，Rat 经测试应用：WB，IHC-P，IHC-Fr，IF/ICC Uniprot No.：Q86WV6 Human ；Q3TBT3 Mouse；F1M391 Rat 抗原：Recombinant protein within human STING aa 117-379. 阳性对照：HDLM-2 cell lysate, THP-1 cell lysate, HT-29 cell lysate, HepG2 cell lysate, HaCaT cell lysate, HL-60 cell lysate, HEK-293 cell lysate, K-562 cell lysate, A20 cell lysate, C2C12 cell lysate, EL4 cell lysate, Rat thymus tissue lysate, human lung tissue, human tonsil tissue, THP-1, PC-12. 应用： WB：1:200-2000 IHC-P/IHC-Fr：1:200-1000 IF/ICC： 1:50-200 存储形式：Liquid 存储液：PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. 储存温度：-20℃
Western blot analysis of STING on different lysates with Rabbit Monoclonal antibody（PC-83782) at 1/1,000 dilution.
Immunocytochemistry analysis of THP-1 cells labeling STING with Rabbit Monoclonal STING antibody （PC-83782) at 1/100 dilution.
Immunocytochemistry analysis of PC-12 cells labeling STING with Rabbit Monoclonal STING antibody （PC-83782) at 1/100 dilution.
Immunohistochemical analysis of paraffin-embedded human lung tissue with Rabbit Monoclonal STING antibody （PC-83782) at 1/4,000 dilution and competitor's antibody at 1/4,000 dilution.
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| 存储温度 | -20℃ |
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