产品描述：Recombinant Mouse Interleukin-15 is produced by our Mammalian expression system and the target gene encoding Asn49-Ser162 is expressed.

蛋白编号：P48346-1

别名：IL-15 Protein, Mouse; Il15 Protein, Mouse

分子量：The recombinant Mouse IL15 comprises 116 amino acids and has a predicted molecular mass of 13.41 kDa. It migrates as approximately 26.7 kDa and 23.5 kDa band in SDS-PAGE under reducing conditions.

溶剂：Lyophilized from sterile PBS, 10% trehalose, pH 7.4.

内毒素：< 1 EU/µg as determined by LAL test.

干粉复溶：

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.

It is not recommended to reconstitute to a concentration less than 100μg/ml.

Dissolve the lyophilized protein in distilled water.

Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

产品背景：The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietic receptor subunits and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively, spliced transcript variants of this gene have been reported.

保存条件：Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.

Reconstituted protein solution can be stored at 2-8°C for 2-7 days.

Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.