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Rabbit Monoclonal IP3 Receptor Antibody

目录号: PC-78364

Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.

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规格 价格 库存
50ul 1800.00 现货
100ul 3200.00 现货

基本信息

名称:兔单克隆IP3R抗体

描述:Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.

克隆:单克隆

别称:4 antibody

5-trisphosphate receptor antibody

5-trisphosphate receptor type 1 antibody

DKFZp313E1334 antibody

DKFZp313N1434 antibody

inositol 1 4 5 triphosphate receptor type 1 antibody

Inositol 1 4 5 trisphosphate Receptor Type 1 antibody

Inositol 1 antibody

InsP3R1 antibody

IP3 antibody

IP3 receptor antibody

IP3 receptor isoform 1 antibody

IP3R 1 antibody

IP3R antibody

IP3R1 antibody

ITPR 1 antibody

Itpr1 antibody

ITPR1_HUMAN antibody

SCA15 antibody

SCA16 antibody

SCA29 antibody

Type 1 inositol 1 4 5 trisphosphate receptor antibody

Type 1 inositol 1 antibody

Type 1 InsP3 receptor antibody

纯化方式:Protein A affinity purified.

宿主:Rabbit/IgG

种属反应性:Human,Mouse,Rat

经测试应用:WB,IHC-P/IHC-Fr

浓度:1mg/ml

预测分子量:314kDa

抗原:Recombinant protein within Human IP3 Receptor aa 2190-2280 / 2758.

阳性对照:Rat brain tissue lysate, Mouse brain tissue lysate, human cerebellum tissue, mouse cerebellum tissue, rat cerebellum tissue.

应用:  WB:500-2000      IHC-P/IHC-Fr:1:100-500  

存储形式:Liquid

存储液:1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

储存温度:-20℃

 

Western blot analysis of IP3 Receptor on different lysates with Rabbit Monoclonal IP3 Receptor Antibody at 1/1,000 dilution.
Lane 1: Rat brain tissue lysate
Lane 2: Mouse brain tissue lysate
Lysates/proteins at 40 µg/Lane.
Predicted band size: 314 kDa
Observed band size: 314 kDa
Exposure time: 3 minutes; ECL: PC-90002.
4-20% SDS-PAGE gel.

 

 

 

 

 

Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue with Rabbit Monoclonal IP3 Receptor Antibody at 1/1,000 dilution.

 

 

 

 

 

 

 

 

 

 

Application: IHC-Fr
Species: Mouse
Site: Cerebellum
Sample: Frozen section
Antibody concentration: 1/500
Antigen retrieval: The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for about 2 minutes in microwave oven.

 

 

 

 

 

Application: IHC-Fr
Species: Rat
Site: cerebellum
Sample: Frozen section
Antibody concentration: 1/500
Antigen retrieval: Not required

 

 

存储温度 -20℃

相关说明文档

储备液配置

注:请根据所选浓度进行配置储备液,配置好储备液后进行分装低温保存,避免反复冻融!PCM提供多种溶剂,如:DMSO(PC-57930);玉米油(PC-86094);棉籽油(PC-30875)等

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