Rabbit Monoclonal Caldesmon Antibody
Caldesmon is a protein that in humans is encoded by the CALD1 gene. Caldesmon is a calmodulin binding protein. Like calponin, caldesmon tonically inhibits the ATPase activity of myosin in smooth muscle. This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca++-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca++-dependent inhibition of smooth muscle contraction.
| 规格 | 价格 | 库存 |
|---|---|---|
| 50ul | 2200.00 | 现货 |
| 100ul | 4000.00 | 现货 |
基本信息
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名称：兔单克隆Caldesmon抗体 描述：Caldesmon is a protein that in humans is encoded by the CALD1 gene. Caldesmon is a calmodulin binding protein. Like calponin, caldesmon tonically inhibits the ATPase activity of myosin in smooth muscle. This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca++-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca++-dependent inhibition of smooth muscle contraction. 克隆：单克隆 别称：CAD antibody CALD 1 antibody CALD1 antibody CALD1_HUMAN antibody Caldesmon 1 antibody Caldesmon 1 Isoform 1 antibody Caldesmon 1 Isoform 2 antibody Caldesmon 1 Isoform 3 antibody Caldesmon 1 Isoform 4 antibody Caldesmon 1 Isoform 5 antibody Caldesmon antibody Caldesmon1 antibody CDM antibody H CAD antibody HCAD antibody L CAD antibody LCAD antibody MGC21352 antibody NAG22 antibody 纯化方式：Protein A affinity purified. 宿主：Rabbit/IgG 种属反应性：Human，Mouse，Rat 经测试应用：WB，IHC-P，IHC-Fr，IF/ICC，IP 浓度：1mg/ml 分子量：93 kDa Uniprot No.：SwissProt: Q05682 Human SwissProt: Q62736 Rat Unigene: 308134 Mouse 抗原：Synthetic peptide within Human Caldesmon aa 744-793 / 793. 阳性对照：NIH/3T3 cell lysates, NIH/3T3, C6, human kidney tissue, mouse kidney tissue, rat kidney tissue. 应用： WB：1:500-1000 IHC-P/IHC-Fr：1:100-500 IF/ICC： 1:50-200 IP：Use at an assay dependent concentration. 存储形式：Liquid 存储液：TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. 储存温度：-20℃
Western blot analysis of Caldesmon on NIH/3T3 cell lysates with Rabbit anti-Caldesmon antibody at 1/500 dilution.
Immunocytochemistry analysis of NIH/3T3 cells labeling Caldesmon with Rabbit anti-Caldesmon antibody at 1/100 dilution.
Immunohistochemical analysis of paraffin-embedded human kidney tissue with Rabbit anti-Caldesmon antibody at 1/200 dilution. |
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| 存储温度 | -20℃ |
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