Rabbit Monoclonal FOXO1A Antibody_常用产品-PlantChemMed

Rabbit Monoclonal FOXO1A Antibody

目录号： PC-76982

FKHR (for forkhead in rhabdomyosarcoma) and FKHRL1 are members of the forkhead family of transcription factors. Transcriptional activation of FKHR proteins is regulated by the serine/threonine kinase Akt1, which phosphorylates FKHRL1 and results in FKHRL1 associating with 14-3-3 proteins and being retained in the cytoplasm. Induction of apoptosis or withdrawal of growth factors stimulates dephosphorylation and nuclear translocation of FKHR proteins, leading to FKHR-induced gene-specific transcriptional activation. FKHR, also designated forkhead box protein O1A (FOXO1), is a ubiquitously expressed protein that shuttles between the cytoplasm and nucleus.

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规格	价格	库存
50ul	1800.00	现货
100ul	3200.00	现货

基本信息

名称：兔单克隆FOXO1抗体

描述：FKHR (for forkhead in rhabdomyosarcoma) and FKHRL1 are members of the forkhead family of transcription factors. Transcriptional activation of FKHR proteins is regulated by the serine/threonine kinase Akt1, which phosphorylates FKHRL1 and results in FKHRL1 associating with 14-3-3 proteins and being retained in the cytoplasm. Induction of apoptosis or withdrawal of growth factors stimulates dephosphorylation and nuclear translocation of FKHR proteins, leading to FKHR-induced gene-specific transcriptional activation. FKHR, also designated forkhead box protein O1A (FOXO1), is a ubiquitously expressed protein that shuttles between the cytoplasm and nucleus.

克隆：单克隆

别称：

FKH 1 antibody

FKH1 antibody

FKHR antibody

Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma) antibody

Forkhead box O1 antibody

Forkhead box protein O1 antibody

Forkhead box protein O1A antibody

Forkhead in rhabdomyosarcoma antibody

Forkhead, Drosophila, homolog of, in rhabdomyosarcoma antibody

FoxO transcription factor antibody

foxo1 antibody

FOXO1_HUMAN antibody

FOXO1A antibody

OTTHUMP00000018301 antibody

纯化方式：Protein A affinity purified.

宿主：Rabbit/IgG

种属反应性：Human，Mouse，Rat

经测试应用：WB，IHC-P，IF/ICC

浓度：1mg/ml

预测分子量：70kDa（实际观察：100kDa）

RRID： AB_3069795

抗原：Synthetic peptide within Human FOXO1A aa 301-350 / 655.

阳性对照：THP-1 cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, HeLa, NIH/3T3, human tonsil tissue, human breast carcinoma tissue, mouse brain tissue, mouse heart tissue, rat brain tissue, rat heart tissue.

应用： WB：1:1000-2000 IHC-P：1:50-100 IF/ICC： 1:50-100

存储形式：Liquid

存储液：1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

储存温度：-20℃

Western blot analysis of FOXO1A on different lysates with Rabbit anti-FOXO1A antibody at 1/5,000 dilution.

Lane 1: THP-1 cell lysate (15 µg/Lane)
Lane 2: Jurkat cell lysate (15 µg/Lane)
Lane 3: NIH/3T3 cell lysate (15 µg/Lane)
Lane 4: PC-12 cell lysate (15 µg/Lane)
Lane 5: Mouse brain tissue lysate (20 µg/Lane)
Lane 6: Rat brain tissue lysate (20 µg/Lane)