蛋白编号：P26441

分子量：22.93KDa

表观分子量：25KDa，reducing conditions

来源：Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 6% Sucrose, 4% Mannitol, 0.05% Tween 80, pH 8.0.

内毒素：Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

溶解：Always centrifuge tubes before opening.Do not mix by vortex or pipetting.

          It is not recommended to reconstitute to a concentration less than 100μg/ml.

          Dissolve the lyophilized protein in distilled water.

          Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 

存储温度：  Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.

                   Reconstituted protein solution can be stored at 2-8°C for 2-7 days.

                   Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品介绍：Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.