Rat Monoclonal CD40 antibody
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
| 规格 | 价格 | 库存 |
|---|---|---|
| 50ug | 1800.00 | 15个工作日 |
| 100ug | 3200.00 | 15个工作日 |
基本信息
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名称：大鼠单克隆CD40抗体 描述：CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. 克隆：单克隆 别称：Bp50 antibody TNFRSF5 antibody 纯化方式：Protein A affinity purified. 免疫原：Recombinant mouse CD40 protein 宿主：Rat/IgG2a, κ 种属反应性：Mouse 经测试应用：IHC-Fr 浓度：0.5mg/ml 应用： IHC-Fr：1:50-500 存储形式：Liquid 存储液：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. 储存温度：2-8℃
Balb/C mouse frozen spleen tissue slices were fixed with 4% PFA for ten minutes and blocked with 5% FBS for 30 minutes.
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| 存储温度 | 2-8℃ |
相关说明文档
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