Rimonabant
(SR141716)Rimonabant (SR141716) 是大麻素受体 1 (CB1) 高效的、选择性的、能透过血脑屏障的拮抗剂
CAS NO.：168273-06-1
| 规格 | 价格 | 库存 |
|---|---|---|
| 10mg | 500.00 | 现货 |
| 25mg | 1000.00 | 现货 |
| 50mg | 1800.00 | 现货 |
| 100mg | 2800.00 | 现货 |
基本信息
|
Rimonabant is a potent and selective cannabinoid (CB) receptor 1 antagonist (Kis = 5.6 and >1,000 nM for CB1 and CB2, respectively). In rodent models, rimonabant induces lipolysis, reduces hepatomegaly, decreases body weight, and improves dyslipidemia by reducing triglyceride, free fatty acid, and total cholesterol levels and by increasing HDL/LDL ratios.Rimonabant elicits antiproliferative and immunomodulatory effects (e.g., cell cycle arrest, increased expression of IκB and phosphorylated Akt, and decreased expression of NF-κB, phosphorylated ERK1/2, COX-2, and iNOS) in vitro. |
|
| CAS | 168273-06-1 |
| 分子量 | 463.79 |
| 分子式 |
C22H21Cl3N4O |
| 溶剂 | DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 2.1561 mL | 10.7807 mL | 21.5615 mL |
| 5 mM | 0.4312 mL | 2.1561 mL | 4.3123 mL |
| 10 mM | 0.2156 mL | 1.0781 mL | 2.1561 mL |
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