Rabbit Monoclonal SNAP25 antibody
Synaptosomal-Associated Protein, 25kDa (SNAP-25) is a Target Soluble NSF (N-ethylmaleimide-sensitive factor) Attachment Protein Receptor (t-SNARE) protein. SNAP-25 is a component of the trans-SNARE complex, which accounts for membrane fusion specificity and directly executes fusion by forming a tight complex that brings the synaptic vesicle and plasma membranes together. Molecular machinery driving exocytosis in neuromediator release. The core SNARE complex is formed by four α-helices contributed by synaptobrevin, syntaxin and SNAP-25. Synaptotagmin serves as a Ca2+ sensor and intimately regulates SNARE zipping. SNAP-25, a Q-SNARE protein, is anchored to the cytosolic face of membranes via palmitoyl side chains covalently bound to cysteine amino acid residues in the central linker domain of the molecule.
| 规格 | 价格 | 库存 |
|---|---|---|
| 50ul | 1800.00 | 现货 |
| 100ul | 3200.00 | 现货 |
基本信息
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名称:兔单克隆 SNAP25 抗体 描述:Synaptosomal-Associated Protein, 25kDa (SNAP-25) is a Target Soluble NSF (N-ethylmaleimide-sensitive factor) Attachment Protein Receptor (t-SNARE) protein. SNAP-25 is a component of the trans-SNARE complex, which accounts for membrane fusion specificity and directly executes fusion by forming a tight complex that brings the synaptic vesicle and plasma membranes together. Molecular machinery driving exocytosis in neuromediator release. The core SNARE complex is formed by four α-helices contributed by synaptobrevin, syntaxin and SNAP-25. Synaptotagmin serves as a Ca2+ sensor and intimately regulates SNARE zipping. SNAP-25, a Q-SNARE protein, is anchored to the cytosolic face of membranes via palmitoyl side chains covalently bound to cysteine amino acid residues in the central linker domain of the molecule. 克隆:单克隆 纯化方式:Protein A affinity purified. 宿主:Rabbit/IgG 浓度:1mg/ml 种属反应性:Human,Mouse,Rat 经测试应用:WB,IHC-P,IF/ICC 预测分子量:23kDa 阳性对照:SH-SY5Y cell lysate, Neuro-2a cell lysate, human brain tissue lysate, SH-SY5Y, human brain tissue, mouse brain tissue, rat brain tissue. 抗原:Recombinant protein within Human SNAP25 aa 51-150 / 206. 应用: WB:1:500-2000 IHC-P:1:500-1000 ICC/IF:1:100 存储形式:Liquid 别名:bA416N4.2 antibody Bdr antibody CMS18 antibody dJ1068F16.2 antibody FLJ23079 antibody HGNC:11132 antibody MGC105414 antibody MGC139754 antibody Resistance to inhibitors of cholinesterase 4 homolog antibody RIC 4 antibody 亚细胞定位:Cytoplasm, perinuclear region, Cell membrane; Lipid-anchor, Synapse, synaptosome, Photoreceptor inner segment. 存储液:1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. 储存温度:-20℃
Western blot analysis of SNAP25 on different lysates with Rabbit anti-SNAP25 antibody at 1/2,000 dilution.
Immunohistochemical analysis of paraffin-embedded human brain tissue with Rabbit anti-SNAP25 antibody at 1/500 dilution.
Immunocytochemistry analysis of SH-SY5Y cells labeling SNAP25 with Rabbit anti-SNAP25 antibody at 1/100 dilution. |
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| 存储温度 | -20℃ |
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