Tadalafil
Tadalafil(IC-351)是PDE5抑制剂
CAS NO.：171596-29-5
| 规格 | 价格 | 库存 |
|---|---|---|
| 50mg | 650.00 | 现货 |
| 100mg | 1000.00 | 现货 |
| 500mg | 3800.00 | 现货 |
基本信息
|
Tadalafil is a potent inhibitor of phosphodiesterase 5 (PDE5; IC50 = 1.2 nM). It is selective for PDE5 over PDE1-4 and 7-10 (IC50s = 9.2-280 μM), however, it does also inhibit PDE11 (IC50 = 11 nM). In vivo, tadalafil (10 mg/kg) decreases production of the proinflammatory cytokines TNF-α, IL-1β, and IL-6 and improves renal function in a rat model of ischemia/reperfusion injury.It also reduces development of tobacco smoke-induced emphysema and pulmonary hypertension in mice.Formulations containing tadalafil have been used to treat erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction. |
|
| CAS | 171596-29-5 |
| 分子量 | 389.4 |
| 分子式 |
C22H19N3O4 |
| 溶剂 | DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 2.5681 mL | 12.8403 mL | 25.6805 mL |
| 5 mM | 0.5136 mL | 2.5681 mL | 5.1361 mL |
| 10 mM | 0.2568 mL | 1.2840 mL | 2.5681 mL |
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