Herbacetin; 3,4',5,7,8-pentahydroxyflavone
Herbacetin is a flavonol compound, and a natural inhibitor of E.coli β-glucuronidase. Herbacetin inhibits inducible nitric oxide synthase via JNK and nuclear factor-κB in LPS-stimulated RAW264.7 cells. Molecular docking study of flavonoid compounds as an inhibitor of β-ketoacyl acyl carrier proteinsynthase II of Pseudomonas aeruginosa.
CAS NO.：527-95-7
| 规格 | 价格 | 库存 |
|---|---|---|
| 5mg | 1850.00 | 现货 |
| 10mg | 3450.00 | 现货 |
| 20mg | 5800.00 | 现货 |
基本信息
|
Herbacetin, a novel Met inhibitor with a potential utility in cancer therapeutics, suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting c-Met and Akt phosphorylation. Herbacetin exerts an anti-inflammatory effect through suppression of LPS-induced JNK and NF-κB signaling pathways and diminished production of proinflammatory cytokines and mediators. Herbacetin also has a strong ability to scavenge free radical and inhibit oxidative protein damage. |
|
| CAS | 527-95-7 |
| 分子量 | 302.24 |
| 分子式 |
C15H10O7 |
| 溶剂 | DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 3.3086 mL | 16.5431 mL | 33.0863 mL |
| 5 mM | 0.6617 mL | 3.3086 mL | 6.6173 mL |
| 10 mM | 0.3309 mL | 1.6543 mL | 3.3086 mL |
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