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Lovastatin

目录号: PC-00471

Lovastatin (Simvastatin EP Impurity E) is an antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase.

CAS NO.:75330-75-5

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规格 价格 库存
10mg 300.00 现货
50mg 500.00 现货
100mg 800.00 现货

基本信息

Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, has a direct cellular effect independent of a cholesterol-lowering effect and delays the onset and progression of diabetic nephropathy. It has a potential application to treat PD via antioxidant effect, and it promotes fibrosis and epithelial to mesenchymal transition, by regulating the production of CCN2 in human gingival fibroblasts.

CAS 75330-75-5
分子量 404.54
分子式 C₂₄H₃₆O₅
溶剂 DMSO
纯度 98%
存储温度 -20℃

相关说明文档

储备液配置

浓度 体积 质量
1mg 5mg 10mg
1 mM 2.4719 mL 12.3597 mL 24.7194 mL
5 mM 0.4944 mL 2.4719 mL 4.9439 mL
10 mM 0.2472 mL 1.2360 mL 2.4719 mL
注:请根据所选浓度进行配置储备液,配置好储备液后进行分装低温保存,避免反复冻融!PCM提供多种溶剂,如:DMSO(PC-57930);玉米油(PC-86094);棉籽油(PC-30875)等

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