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Geissoschizine methyl ether

目录号: PC-00427

This product is isolated and purified from the hooks of Uncariae Ramulus et Uncus.

CAS NO.:60314-89-8

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规格 价格 库存
5mg 1500.00 现货
10mg 2200.00 现货
20mg 3800.00 现货

基本信息

Geissoschizine methyl ether is a potent serotonin ₁A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan. Geissoschizine methyl ether has vasorelaxant effect, which is composed of two different mechanisms: endothelial dependency with nitric oxide and endothelial independency with voltage-dependent Ca(2+)-channel blocking.Geissoschizine methyl ether has third-generation antipsychotic-like actions at the dopamine and serotonin receptors. Geissoschizine methyl ether is a strong acetylcholinesterase (AChE) inhibitor, it inhibited 50% of AChE activity at concentrations of 3.7 ± 0.3 ug/mL. Geissoschizine methyl ether protects neurons from oxidative toxicity by shifting energy metabolism from mitochondrial respiration to glycolysis.

CAS 60314-89-8
分子量 366.45
分子式 C₂₂H₂₆N₂O₃
溶剂 DMSO
纯度 98%
存储温度 -20℃

相关说明文档

储备液配置

浓度 体积 质量
1mg 5mg 10mg
1 mM 2.7289 mL 13.6444 mL 27.2889 mL
5 mM 0.5458 mL 2.7289 mL 5.4578 mL
10 mM 0.2729 mL 1.3644 mL 2.7289 mL
注:请根据所选浓度进行配置储备液,配置好储备液后进行分装低温保存,避免反复冻融!PCM提供多种溶剂,如:DMSO(PC-57930);玉米油(PC-86094);棉籽油(PC-30875)等

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