Chelidonine
Chelidonine is an isoquinoline alkaloid isolated from Chelidonium majus L., causes G2/M arrest and induces caspase-dependent and caspase-independent apoptosis, with anticancer and antiviral activity。
CAS NO.：476-32-4
| 规格 | 价格 | 库存 |
|---|---|---|
| 1mg | 800.00 | 现货 |
| 5mg | 1880.00 | 现货 |
| 10mg | 3200.00 | 现货 |
基本信息
|
Chelidonine is a promising model compound for overcoming MDR and for enhancing cytotoxicity of chemotherapeutics, especially against leukaemia cells, its efficacy needs to be confirmed in animal models. Chelidonine may be a potential therapeutic agent against metastasis of invasive human cancer cells, exhibits anti‑migratory and anti‑invasive effects in MDA‑MB‑231 cells, by suppressing COL‑I‑induced integrin signaling, through inhibiting the formation of the IPP complex and subsequent down‑regulation of IPP downstream signaling molecules, such as Akt and ERK1/2. |
|
| CAS | 476-32-4 |
| 分子量 | 353.37 |
| 分子式 | C₂₀H₁₉NO₅ |
| 溶剂 | DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 2.8299 mL | 14.1495 mL | 28.2990 mL |
| 5 mM | 0.5660 mL | 2.8299 mL | 5.6598 mL |
| 10 mM | 0.2830 mL | 1.4149 mL | 2.8299 mL |
相关产品推荐
Luteolin is a non-selective phisphodiesterase PDE inhibitor
Quercetin is one of the most prominent dietary antioxidants,
Propranolol hydrochloride 是一种非选择性的肾上腺素受体拮抗剂，Propranolol hydr
α-solanine 是马铃薯中的一种生物活性成分，Alpha-Solanine可改变脂肪和肠中的抗氧化酶活性，MDA和
浏览历史产品
10mM非必须氨基酸（100X）经无菌过滤处理，可直接用于细胞培养实验，可按照100倍稀释使用亦可根据实验要求自行调整工
Rosavin possesses anti-fatigue, antidepressant and anxiolyti
Chikusetsusaponin IV可能通过Fas/FasL途径缓解皮肤过度凋亡细胞死亡引起的皮肤症状。
Isorhyncophylline and rhyncophylline can directly inhibit th