Geraniin
Geraniin is a TNF-α releasing inhibitor with numerous activities including anticancer, anti-inflammatory, and anti-hyperglycemic activities
CAS NO.：60976-49-0
| 规格 | 价格 | 库存 |
|---|---|---|
| 5mg | 850.00 | 现货 |
| 10mg | 1550.00 | 现货 |
| 20mg | 2800.00 | 现货 |
基本信息
|
Geraniin is a TNF-α releasing inhibitor with numerous activities including anticancer, anti-inflammatory, has anti-oxidant , and anti-hyperglycemic activities, with an IC50 of 43 μM. Geraniin presents radioprotective effects by regulating DNA damage on splenocytes, exerting immunostimulatory capacities and inhibiting apoptosis of radiosensitive immune cells and jejunal crypt cells. Geraniin induces Nrf2-mediated expression of antioxidant enzymes HO-1 and NQO1, presumably via PI3K/AKT and ERK1/2 signaling pathways, thereby protecting cells from H2O2-induced oxidative cell death. |
|
| CAS | 60976-49-0 |
| 分子量 | 952.64 |
| 分子式 | C₄₁H₂₈O₂₇ |
| 溶剂 | DMSO |
| 纯度 | 96% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
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浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 1.0497 mL | 5.2486 mL | 10.4971 mL |
| 5 mM | 0.2099 mL | 1.0497 mL | 2.0994 mL |
| 10 mM | 0.1050 mL | 0.5249 mL | 1.0497 mL |
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