Bufotaline
Bufotalin is a component of Bufo bufo gargarizans which acts as an anti-tumor agent.
CAS NO.：471-95-4
| 规格 | 价格 | 库存 |
|---|---|---|
| 5mg | 700.00 | 现货 |
| 10mg | 1300.00 | 现货 |
| 20mg | 2400.00 | 现货 |
基本信息
|
Bufotalin is a cardiotoxic bufanolide steroid, cardiac glycoside analogue. Bufotalin has anti-cancer activity, it can induce apoptosis in Hep 3B cells, and caspase-8 inhibitor (Z-IETD) or wide-ranging caspase inhibitor (Z-VAD) significantly suppresses the bufotalin-induced apoptosis. Bufotalin is a powerful sensitizer of death receptor-induced apoptosis in cancer cells, it promotes death receptor-mediated cell death, especially TRAIL-induced apoptosis, through activation of caspase-3 and PARP-1. |
|
| CAS | 471-95-4 |
| 分子量 | 444.56 |
| 分子式 |
C26H36O6 |
| 溶剂 | DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 2.2494 mL | 11.2471 mL | 22.4942 mL |
| 5 mM | 0.4499 mL | 2.2494 mL | 4.4988 mL |
| 10 mM | 0.2249 mL | 1.1247 mL | 2.2494 mL |
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