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Cinobufagin

  (Cinobufagine)
目录号: PC-00234

Cinobufagine is a major component of cinobufacini (huachansu), is an important cardenolidal steroid. Cinobufagine was shown to exhibit potent anti-cancer effects.

CAS NO.:470-37-1

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规格 价格 库存
5mg 1000.00 现货
10mg 1900.00 现货
20mg 3500.00 现货

基本信息

Cinobufagin, a kind of Chinese materia medica with antitumor effect, is widely used in clinical practice, especially in anti-liver cancer, it also has anti-hepatitis B virus activity . Cinobufagin inhibits the proliferation and induces apoptosis, may be related to the mitochondria-mediated pathway and GSK-3β/NF-κB pathway. Cinobufagin can significantly relieve cancer pain in mice and raised their pain threshold, mainly upregulating the expression levels of β -END and μ -OR in the hind paw tumor and adjacent tissue.Cinobufagin and bufalin exhibit cardiotonic and natriuretic activities, they also have inhibitory effects on steroidogenesis of aldosterone and cortisol.

CAS 470-37-1
分子量 442.54
分子式 C₂₆H₃₄O₆
溶剂 DMSO
纯度 95%
存储温度 -20℃

相关说明文档

储备液配置

浓度 体积 质量
1mg 5mg 10mg
1 mM 2.2597 mL 11.2984 mL 22.5968 mL
5 mM 0.4519 mL 2.2597 mL 4.5194 mL
10 mM 0.2260 mL 1.1298 mL 2.2597 mL
注:请根据所选浓度进行配置储备液,配置好储备液后进行分装低温保存,避免反复冻融!PCM提供多种溶剂,如:DMSO(PC-57930);玉米油(PC-86094);棉籽油(PC-30875)等

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