Daurisoline
( (R,R)-Daurisoline)Daurisoline is a bisbenzylisoquinoline alkaloid isolated from Menispermum dauricum and displays antiarrythmic effects.
CAS NO.:70553-76-3
规格 | 价格 | 库存 |
---|---|---|
5mg | 700.00 | 现货 |
10mg | 1200.00 | 现货 |
20mg | 2200.00 | 现货 |
基本信息
Daurisoline is a hERG inhibitor and also an autophagy blocker.Daurisoline has antiarrhythmic effects, it( at concentrations below 30 uM) exerts a blocking effect on hERG, but does not affect the expression and function of the hERG channel, it also can inhibit early afterdepolarizations (EADs) which may be associated with its blockade effects on I(Ca-L). Daurisoline and its isomers show cytoprotective effects on ischemic injury in cultured pheochromocytoma (PC12) cells, which are mediated by blocking Ca2+ influx into cells. |
|
CAS | 70553-76-3 |
分子量 | 610.74 |
分子式 | C₃₇H₄₂N₂O₆ |
溶剂 | DMSO |
纯度 | 98% |
存储温度 | -20℃ |
相关说明文档
储备液配置
浓度
体积
质量
|
1mg | 5mg | 10mg |
1 mM | 1.6374 mL | 8.1868 mL | 16.3736 mL |
5 mM | 0.3275 mL | 1.6374 mL | 3.2747 mL |
10 mM | 0.1637 mL | 0.8187 mL | 1.6374 mL |
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