Lovastatin
(洛伐他汀)Lovastatin (Simvastatin EP Impurity E) is an antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase.
CAS NO.：75330-75-5
| 规格 | 价格 | 库存 |
|---|---|---|
| 10mg | 300.00 | 现货 |
| 50mg | 500.00 | 现货 |
| 100mg | 800.00 | 现货 |
基本信息
|
Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, has a direct cellular effect independent of a cholesterol-lowering effect and delays the onset and progression of diabetic nephropathy. It has a potential application to treat PD via antioxidant effect, and it promotes fibrosis and epithelial to mesenchymal transition, by regulating the production of CCN2 in human gingival fibroblasts. |
|
| CAS | 75330-75-5 |
| 分子量 | 404.54 |
| 分子式 | C₂₄H₃₆O₅ |
| 溶剂 | DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 2.4719 mL | 12.3597 mL | 24.7194 mL |
| 5 mM | 0.4944 mL | 2.4719 mL | 4.9439 mL |
| 10 mM | 0.2472 mL | 1.2360 mL | 2.4719 mL |
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