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Fraxin

  (Fraxoside; Paviin)
目录号: PC-00143

白蜡树内酯的一种糖苷,并具有抗氧化、抗炎和抗转移活性。通过抑制环腺苷酸磷酸二酯酶表现出抗氧化活性。

CAS NO.:524-30-1

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规格 价格 库存
5mg 600.00 现货
10mg 1100.00 现货
20mg 1900.00 现货

基本信息

Fraxin is a coumarin glycoside that has been found in Fraxinus and has anti-inflammatory activity. It inhibits formation of 5-hydroxyeicosatetraenoic acid (5-HETE) from arachidonic acid in rat polymorphonuclear leukocytes when used at concentrations ranging from 1 to 1,000 µM in vitro.Fraxin inhibits production of nitric oxide (NO) in LPS-stimulated RAW 264.7 cells (IC50 = 84.5 µM). It also decreases LPS-induced TNF-α, IL-6, IL-1β, NF-ĸB, and NLRP3 expression in the lung in mouse models of acute lung injury and endotoxic shock when administered at doses ranging from 10 to 40 mg/kg.

CAS 524-30-1
分子量 370.31
分子式 C₁₆H₁₈O₁₀
溶剂 DMSO
纯度 98%
存储温度 -20℃

相关说明文档

储备液配置

浓度 体积 质量
1mg 5mg 10mg
1 mM 2.7004 mL 13.5022 mL 27.0044 mL
5 mM 0.5401 mL 2.7004 mL 5.4009 mL
10 mM 0.2700 mL 1.3502 mL 2.7004 mL
注:请根据所选浓度进行配置储备液,配置好储备液后进行分装低温保存,避免反复冻融!PCM提供多种溶剂,如:DMSO(PC-57930);玉米油(PC-86094);棉籽油(PC-30875)等

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