Ginsenoside Rd
Ginsenoside RD has been shown to attenuate tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after forebrain ischemia. This could be used to counter the risk of developing post-stroke dementia.
CAS NO.：52705-93-8
| 规格 | 价格 | 库存 |
|---|---|---|
| 5mg | 600.00 | 现货 |
| 10mg | 1000.00 | 现货 |
| 20mg | 1750.00 | 现货 |
基本信息
|
Ginsenoside Rd, a minor ginseng saponin, has several pharmacological activities such as immunosuppressive activity, anti-inflammatory activity, immunological adjuvant, anti-cancer activity and wound-healing activity. Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells. Rd inhibits expression of COX-2 and iNOS mRNA. Rd also inhibits Ca2+ influx. Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively. |
|
| CAS | 52705-93-8 |
| 分子量 | 947.15 |
| 分子式 |
C48H82O18 |
| 溶剂 | DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 1.0558 mL | 5.2790 mL | 10.5580 mL |
| 5 mM | 0.2112 mL | 1.0558 mL | 2.1116 mL |
| 10 mM | 0.1056 mL | 0.5279 mL | 1.0558 mL |
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