Jolkinolide B
Jolkinolide B, a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud, is known to induce apoptosis in cancer cells
CAS NO.：37905-08-1
| 规格 | 价格 | 库存 |
|---|---|---|
| 5mg | 2000.00 | 现货 |
| 10mg | 3600.00 | 现货 |
| 20mg | 4800.00 | 现货 |
基本信息
|
1. Jolkinolide B can induce neuroendocrine differentiation of human prostate LNCaP cancer cell line. 2. Jolkinolide B can induce apoptosis in MDA-MB-231 cells through inhibition of the PI3K/Akt signaling pathway. 3. Jolkinolide B has potent anti-inflammatory activities, the mechanism may be attributed to its suppression of NF-κB and activation. 4. Jolkinolide B exhibits significant antitumor activity, it is able to enhance apoptosis of human leukemic HL-60 and THP-1 cells, at least in part, through downregulation of JAK2/STAT3 and bcl-2, and upregulation of Bax and cytosolic cytochrome c. |
|
| CAS | 37905-08-1 |
| 分子量 | 330.42 |
| 分子式 |
C20H26O4 |
| 溶剂 | DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 3.0265 mL | 15.1323 mL | 30.2645 mL |
| 5 mM | 0.6053 mL | 3.0265 mL | 6.0529 mL |
| 10 mM | 0.3026 mL | 1.5132 mL | 3.0265 mL |
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