Lovastatin
Lovastatin (Simvastatin EP Impurity E) is an antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase.
CAS NO.:75330-75-5
规格 | 价格 | 库存 |
---|---|---|
10mg | 300.00 | 现货 |
50mg | 500.00 | 现货 |
100mg | 800.00 | 现货 |
基本信息
Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, has a direct cellular effect independent of a cholesterol-lowering effect and delays the onset and progression of diabetic nephropathy. It has a potential application to treat PD via antioxidant effect, and it promotes fibrosis and epithelial to mesenchymal transition, by regulating the production of CCN2 in human gingival fibroblasts. |
|
CAS | 75330-75-5 |
分子量 | 404.54 |
分子式 | C₂₄H₃₆O₅ |
溶剂 | DMSO |
纯度 | 98% |
存储温度 | -20℃ |
相关说明文档
储备液配置
浓度
体积
质量
|
1mg | 5mg | 10mg |
1 mM | 2.4719 mL | 12.3597 mL | 24.7194 mL |
5 mM | 0.4944 mL | 2.4719 mL | 4.9439 mL |
10 mM | 0.2472 mL | 1.2360 mL | 2.4719 mL |
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