Galangin
(Norizalpinin;3,5,7-Trihydroxyflavone)Galangin is a flavanoid found in Alpinia officinarum, galangal rhizome (Alpinia galanga) and in propolis. Galangin has been show to inhibit proliferation of estrogen receptor-positive MCF-7 human breast cancer cells as well as delay of mammary tumorigenesis.
CAS NO.:548-83-4
规格 | 价格 | 库存 |
---|---|---|
20mg | 650.00 | 现货 |
50mg | 1150.00 | 现货 |
100mg | 2000.00 | 现货 |
基本信息
Galangin is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity. Galangin has anti-proliferation, anti-metastatic, anti-inflammatory, vasorelaxant, antiviral, anti-allergic inflammatory,anti-obesity effects; it may be a potential candidate for the treatment of vitiligo. Galangin can inhibit Topo I activity and reduce the unwinding rate of single stranded DNNA in tumor cells, which plays an important role in induction of A549 and H46 cell apoptosis. Galangin shows an inhibitory effect on acetylcholinesterase (AChE) activity with the IC(50) of 120 microM; it also inhibits ERK, NF-κB-p65 and proinflammatory gene expression. |
|
CAS | 548-83-4 |
分子量 | 270.24 |
分子式 | C₁₅H₁₀O₅ |
溶剂 | DMSO |
纯度 | 98% |
存储温度 | -20℃ |
相关说明文档
储备液配置
浓度
体积
质量
|
1mg | 5mg | 10mg |
1 mM | 3.7004 mL | 18.5021 mL | 37.0041 mL |
5 mM | 0.7401 mL | 3.7004 mL | 7.4008 mL |
10 mM | 0.3700 mL | 1.8502 mL | 3.7004 mL |
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