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Hyodeoxycholic acid

  (HDCA)
目录号: PC-00436

Hyodeoxycholic Acid is isolated from pig bile. Antitumor agent.

CAS NO.:83-49-8

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规格 价格 库存
100mg 500.00 现货
200mg 800.00 现货
500mg 1300.00 现货

基本信息

Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC50 of 31.6 µM in CHO cells. Hyodeoxycholic acid has hypolipidemic effect through regulation of FXR activation, it is a candidate for antiatherosclerotic drug, by significantly increasing the expression of genes involved in cholesterol efflux, such as Abca1, Abcg1,and Apoe,in a macrophage cell line.

CAS 83-49-8
分子量 392.57
分子式 C₂₄H₄₀O₄
溶剂 DMSO
纯度 98%
存储温度 -20℃

相关说明文档

储备液配置

浓度 体积 质量
1mg 5mg 10mg
1 mM 2.5473 mL 12.7366 mL 25.4732 mL
5 mM 0.5095 mL 2.5473 mL 5.0946 mL
10 mM 0.2547 mL 1.2737 mL 2.5473 mL
注:请根据所选浓度进行配置储备液,配置好储备液后进行分装低温保存,避免反复冻融!PCM提供多种溶剂,如:DMSO(PC-57930);玉米油(PC-86094);棉籽油(PC-30875)等

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