Polygalasaponin F
Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa).
CAS NO.：882664-74-6
| 规格 | 价格 | 库存 |
|---|---|---|
| 5mg | 1100.00 | 现货 |
| 10mg | 2000.00 | 现货 |
| 20mg | 3500.00 | 现货 |
基本信息
|
Polygalasaponin F possesses anxiolytic and sedative-hypnotic activities, and has cognition improving and cerebral protective effects. Polygalasaponin F can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Polygalasaponin F can induce long-term potentiation in hippocampal dentate gyrus in anesthetized rats via NMDAR activation mediated by Ca(2+)/calmodulin-dependent kinase II, extracellular signal-regulated kinase and cAMP response element-binding protein signaling pathway. |
|
| CAS | 882664-74-6 |
| 分子量 | 1091.24 |
| 分子式 | C₅₃H₈₆O₂₃ |
| 溶剂 | DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 0.9164 mL | 4.5819 mL | 9.1639 mL |
| 5 mM | 0.1833 mL | 0.9164 mL | 1.8328 mL |
| 10 mM | 0.0916 mL | 0.4582 mL | 0.9164 mL |
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