Cinobufagin
(Cinobufagine)Cinobufagine is a major component of cinobufacini (huachansu), is an important cardenolidal steroid. Cinobufagine was shown to exhibit potent anti-cancer effects.
CAS NO.:470-37-1
规格 | 价格 | 库存 |
---|---|---|
5mg | 1000.00 | 现货 |
10mg | 1900.00 | 现货 |
20mg | 3500.00 | 现货 |
基本信息
Cinobufagin, a kind of Chinese materia medica with antitumor effect, is widely used in clinical practice, especially in anti-liver cancer, it also has anti-hepatitis B virus activity . Cinobufagin inhibits the proliferation and induces apoptosis, may be related to the mitochondria-mediated pathway and GSK-3β/NF-κB pathway. Cinobufagin can significantly relieve cancer pain in mice and raised their pain threshold, mainly upregulating the expression levels of β -END and μ -OR in the hind paw tumor and adjacent tissue.Cinobufagin and bufalin exhibit cardiotonic and natriuretic activities, they also have inhibitory effects on steroidogenesis of aldosterone and cortisol. |
|
CAS | 470-37-1 |
分子量 | 442.54 |
分子式 | C₂₆H₃₄O₆ |
溶剂 | DMSO |
纯度 | 95% |
存储温度 | -20℃ |
相关说明文档
储备液配置
浓度
体积
质量
|
1mg | 5mg | 10mg |
1 mM | 2.2597 mL | 11.2984 mL | 22.5968 mL |
5 mM | 0.4519 mL | 2.2597 mL | 4.5194 mL |
10 mM | 0.2260 mL | 1.1298 mL | 2.2597 mL |
相关产品推荐
Luteolin is a non-selective phisphodiesterase PDE inhibitor
Quercetin is one of the most prominent dietary antioxidants,
Propranolol hydrochloride 是一种非选择性的肾上腺素受体拮抗剂,Propranolol hydr
α-solanine 是马铃薯中的一种生物活性成分,Alpha-Solanine可改变脂肪和肠中的抗氧化酶活性,MDA和
浏览历史产品
Rp-cAMPS triethylammonium salt 是 cAMP 的类似物,可作为 cAMP 诱导的依赖 cA
D-PBS缓冲液(不含钙镁和酚红)通过0.22um过滤器除菌,PH为7.2-7.4
Saikosaponin B4 can selectively inhibit ACTH-induced lipolys
The compund has been isolated from Taxus brevifolia. It is a