Cinobufotalin
Cinobufotalin is used in combination with irinotecan and capecitabine for treating advanced colorectal cancer, study of the clinical curative effect in the treatment of cancer pain, pre-clinical evaluation of cinobufotalin as potential anti-lung cancer agent.
CAS NO.：1108-68-5
| 规格 | 价格 | 库存 |
|---|---|---|
| 5mg | 850.00 | 现货 |
| 10mg | 1400.00 | 现货 |
| 20mg | 2500.00 | 现货 |
基本信息
|
Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent for the multidrug resistance of tumors, it can reverse the adriamycin-resistance in Raji/ADR cells and the expression of P-gp and MRP-1 proteins. Cinobufotalin can promote the dendritic cells(DCs) derived from peripheral blood of patients with chronic hepatitis B to mature and effectively enhance its(the DCs') capabilities, therefore the treatment of cinobufotalin may potentiate the antiviral immunity of the patients with chronic hepatitis B(CHB). |
|
| CAS | 1108-68-5 |
| 分子量 | 458.54 |
| 分子式 | C₂₆H₃₄O₇ |
| 溶剂 | DMSO |
| 纯度 | 98% |
| 存储温度 | -20℃ |
相关说明文档
储备液配置
|
浓度
体积
质量
|
1mg | 5mg | 10mg |
| 1 mM | 2.1808 mL | 10.9042 mL | 21.8083 mL |
| 5 mM | 0.4362 mL | 2.1808 mL | 4.3617 mL |
| 10 mM | 0.2181 mL | 1.0904 mL | 2.1808 mL |
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