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Daurisoline

  ( (R,R)-Daurisoline)
目录号: PC-00171

Daurisoline is a bisbenzylisoquinoline alkaloid isolated from Menispermum dauricum and displays antiarrythmic effects.

CAS NO.:70553-76-3

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规格 价格 库存
5mg 700.00 现货
10mg 1200.00 现货
20mg 2200.00 现货

基本信息

Daurisoline is a hERG inhibitor and also an autophagy blocker.Daurisoline has antiarrhythmic effects, it( at concentrations below 30 uM) exerts a blocking effect on hERG, but does not affect the expression and function of the hERG channel, it also can inhibit early afterdepolarizations (EADs) which may be associated with its blockade effects on I(Ca-L). Daurisoline and its isomers show cytoprotective effects on ischemic injury in cultured pheochromocytoma (PC12) cells, which are mediated by blocking Ca2+ influx into cells.

CAS 70553-76-3
分子量 610.74
分子式 C₃₇H₄₂N₂O₆
溶剂 DMSO
纯度 98%
存储温度 -20℃

相关说明文档

储备液配置

浓度 体积 质量
1mg 5mg 10mg
1 mM 1.6374 mL 8.1868 mL 16.3736 mL
5 mM 0.3275 mL 1.6374 mL 3.2747 mL
10 mM 0.1637 mL 0.8187 mL 1.6374 mL
注:请根据所选浓度进行配置储备液,配置好储备液后进行分装低温保存,避免反复冻融!PCM提供多种溶剂,如:DMSO(PC-57930);玉米油(PC-86094);棉籽油(PC-30875)等

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